Shoulder replacement surgery is an effective intervention that can relieve pain and improve function for people with severe shoulder disorders. The use of shoulder replacement has been steadily increasing over time worldwide because of the expanding range of clinical indications, including osteoarthritis, which is most [...]
Lower limb total joint arthroplasty (TJA) is usually offered to patients to alleviate symptoms of their hip or knee osteoarthritis when conservative management fails. In other orthopaedic conditions, second opinions have been found to result in up to half of the patients initially recommended for [...]
With over 50% of women suffering from at least one episode of urinary tract infection (UTI) each year and an increasing prevalence of antimicrobial resistance, efforts need to be made to clearly identify the evidence supporting potential non-drug interventions. This study aims to compare the [...]
Risk-based stratified care involves selecting treatments according to a participant's risk of persistent disabling pain, to maximise treatment benefit and reduce potential harm and wasted resources associated with unnecessary interventions. The STarTBack approach is a widely known and investigated example of a risk-based stratified care [...]
Recurrence of low back pain is common and a substantial contributor to the disease and economic burden of low back pain. Exercise is recommended to prevent recurrence, but the effectiveness and cost-effectiveness of an accessible and low-cost intervention, such as walking, is yet to be [...]
Clinical care indicators for low back pain can be used to monitor healthcare practices and consequently be used to evaluate success of strategies to improve care quality. The aim of this study was to identify the clinical care indicators that have been used to measure [...]
Atrial fibrillation (AF) is the most common cardiac arrhythmia and a key risk factor for embolic stroke and heart failure, with an increasing global burden as the population continues to age. AF treatment involves stroke prevention, symptom management, and cardiovascular and comorbidity optimisation. Treatment decisions [...]
Surgery can help patients with leg pain caused by sciatica recover faster, but by 12 months outcomes are similar to nonsurgical management. For many the decision to have surgery may require reflection, and patient decision aids are an evidence-based clinical tool that can help guide [...]
Cardiovascular disease (CVD) risk equations are useful to guide treatment decisions for blood pressure and lipid-lowering medications because they identify patients who are at high risk of CVD but do not have either blood pressure or cholesterol measurements above the levels when considering treatment as [...]
This study aims to evaluate the efficacy and cost-effectiveness of sonothrombolysis delivered pre and post primary percutaneous coronary intervention (pPCI) on infarct size assessed by cardiac MRI, in patients presenting with STEMI, when compared against sham procedure. More than a half of patients with successful [...]