Risk Archives - Page 5 of 7 - Wiser Healthcare

Changes in opioid agonist treatment initiation among people prescribed opioids for pain following voluntary and mandatory prescription drug monitoring program implementation: A time series analysis – Louisa Picco et al.

Lucia Marcello2023-12-04T14:13:26+11:00Health policy, Mental Health, Opioids, Pain, Prescribing, Publications, Risk|

Prescription drug monitoring programs (PDMP) are increasingly used to identify people prescribed high-dose opioids. However, little is known about whether PDMPs impact opioid agonist treatment (OAT) uptake, the gold standard for opioid use disorder. This study examined the impact of PDMP implementation on OAT initiation [...]

Artificial Intelligence-Driven Mammography-Based Future Breast Cancer Risk Prediction: A Systematic Review – Cody M. Schopf et al.

Lucia Marcello2023-12-01T15:22:04+11:00AI, Breast cancer, Cancer, Imaging, Publications, Risk, Screening|

The purpose of this study is to summarize the literature regarding the performance of mammography-image based artificial intelligence (AI) algorithms, with and without additional clinical data, for future breast cancer risk prediction.

Gene therapy in cardiology: is a cure for hypertrophic cardiomyopathy on the horizon? – Elizabeth D Paratz et al.

Lucia Marcello2024-06-05T16:06:18+10:00Cardiovascular disease, Genetic testing, Hypertension, Precision medicine, Publications, Risk, Treatment|

Hypertrophic cardiomyopathy (HCM) is the commonest genetic cardiomyopathy world-wide, affecting approximately 1 in 500 individuals. Current therapeutic interventions comprise lifestyle optimisation, medications, septal reduction therapies and rarely cardiac transplantation. Advances in our understanding of disease-causing genetic variants in HCM and their associated molecular mechanisms have [...]

Use of CT, ED presentation and hospitalisations 12 months before and after a diagnosis of cancer in Western Australia: a population-based retrospective cohort study – Ninh Thi Ha et al.

Lucia Marcello2023-12-01T14:21:39+11:00Cancer, Imaging, Overdiagnosis, Overtesting, Publications, Risk, Screening, Treatment|

The present study examines the patterns of hospital and emergency department services in conjunction with both pre and post diagnostic periods of CT use, which has not been evaluated to date in adult patients with cancer. The cohort makes use of whole of population data [...]

Childhood vaccine refusal and what to do about it: a systematic review of the ethical literature – Kerrie Wiley et al.

Lucia Marcello2023-12-01T13:50:01+11:00Big pharma, Ethical considerations, Health policy, Publications, Risk|

Parental refusal of routine childhood vaccination remains an ethically contested area. This systematic review sought to explore and characterise the normative arguments made about parental refusal of routine vaccination, with the aim of providing researchers, practitioners, and policymakers with a synthesis of current normative literature.

Lung cancer screening program factors that influence psychosocial outcomes: A systematic review – Kathleen McFadden et al.

Lucia Marcello2023-12-01T13:39:20+11:00Cancer, Decision aids, Mental Health, Publications, Risk, Screening, Shared decision making|

Lung cancer screening (LCS) programs are being designed and implemented globally. Early data suggests that the psychosocial impacts of LCS are influenced by program factors, but evidence synthesis is needed. This systematic review aimed to elucidate the impact of service-level factors on psychosocial outcomes to [...]

Does mammographic density predict survival in women with invasive breast cancer? The need to account for potential confounding from cancer stage and overdiagnosis – Katie J Bell & Meagan Brennan

Lucia Marcello2023-12-01T12:05:02+11:00Breast cancer, Breast density, Cancer, Publications, Risk, Screening, Treatment|

High breast density on mammography is a well-established risk factor for a breast cancer diagnosis. There is interest in whether breast density might also predict how aggressive a breast cancer is, including the likelihood of causing death. If mammographic features at the time of cancer [...]

Incorporating a polygenic risk score-triaged coronary calcium score into cardiovascular disease examinations to identify subclinical coronary artery disease (ESCALATE): Protocol for a prospective, nonrandomized implementation trial – Michael P. Gray et al

Lucia Marcello2023-12-01T11:32:51+11:00Cardiovascular disease, Diagnostic system, Publications, Risk|

Identifying and targeting established modifiable risk factors has been a successful strategy for reducing the burden of coronary artery disease (CAD) at the population-level. However, up to 1-in-4 patients who present with ST elevation myocardial infarction do so in the absence of such risk factors. Polygenic risk scores (PRS) [...]

2023 ESC Guidelines for the management of cardiomyopathies – Elena Arbelo et al.

Lucia Marcello2023-12-01T09:39:50+11:00Cardiovascular disease, Clinical guidelines, Genetic testing, Publications, Risk|

The objective of this European Society of Cardiology (ESC) Guideline is to help healthcare professionals diagnose and manage patients with cardiomyopathies according to the best available evidence. Uniquely for relatively common cardiovascular diseases, there are very few randomized controlled clinical trials in patients with cardiomyopathies. [...]

Measures of socioeconomic advantage are not independent predictors of support for healthcare AI: subgroup analysis of a national Australian survey – Emma Kellie Frost et al

Lucia Marcello2023-06-28T15:42:02+10:00AI, Ethical considerations, Health professionals, Publications, Risk|

Applications of artificial intelligence (AI) have the potential to improve aspects of healthcare. However, studies have shown that healthcare AI algorithms also have the potential to perpetuate existing inequities in healthcare, performing less effectively for marginalised populations. Studies on public attitudes towards AI outside of [...]

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