Reporting guidelines can improve dissemination and application of findings and help avoid research waste. Recent studies reveal opportunities to improve primary care (PC) reporting. Despite increasing numbers of guidelines, none exists for PC research. This study aims to prioritise candidate reporting items to inform a [...]
Prioritisation of clinical trials ensures that the research conducted meets the needs of stakeholders, makes the best use of resources and avoids duplication. The aim of this review was to identify and critically appraise approaches to research prioritisation applicable to clinical trials, to inform best [...]
Understanding how people use infographics and their opinion on them has important implications for the design of infographics but has not been investigated. The aim of this study was to describe people’s use of and opinions about infographics summarising health and medical research, preferences for [...]
Empirical evidence suggests data and insights from the clinical practice guidelines and clinical quality registries are not being fully utilised, leaving health service managers, clinicians and providers without clear guidance on how best to improve healthcare delivery. This lack of uptake of existing research knowledge [...]
Harms in clinical trials may be characterised by adverse events (AEs) and adverse reactions. Both terms refer to untoward medical occurrences in a trial participant, but the second term presumes causation and is reserved for events directly attributed to the investigational treatment. Harms reporting in [...]
We aimed to develop a methodological framework for quantifying overdiagnosis that may be used for asymptomatic or symptomatic conditions and used gestational diabetes mellitus as an example of how it may be applied.
The aim of this article was to develop best practice recommendations for economic evaluations alongside future ICU randomised controlled trials (RCTs).
Qualitative research, the analysis of language and other non-numerical data, is critical to applied (including interventional) research. It provides unique insight into peoples' experiences, including those related to healthcare systems, services and programs, in a manner that quantitative methods cannot.
While research oversight is necessary and desirable for some types and elements of research, we must also recognise that research review is itself a healthcare intervention and should therefore be subject to the same evidence-based requirements demanded of other healthcare interventions. Inefficiencies in any part of [...]
Who is responsible for promoting the research needed to address treatment uncertainties and thus reduce harmful elements of healthcare? A wide range of people could be considered to share in this collective responsibility, including research funders, researchers, health professionals and patient groups. A particularly heavy [...]