In the past decade, numerous ethical frameworks have been developed to support public health decision-making in challenging areas. Before the COVID-19 pandemic began, members of the authorship team were involved in research programmes, in which the development of ethical frameworks was planned, to guide (a) [...]
This is a comment on "Public Engagement through Inclusive Deliberation: The Human Genome International Commission and Citizens' Juries." Am J Bioeth. 2023 Dec;23(12):66-76.
You order a computed tomography pulmonary angiogram (CTPA) for a patient with suspected pulmonary thromboembolism. The radiology report states that no pulmonary thromboembolism is seen but notes an unrelated lung nodule. What should you do with this incidental finding, or “incidentaloma”?
We investigated differences in cumulative incidence of first distant recurrence following non-metastatic breast cancer over a time period when new adjuvant therapies became available in Australia. We conducted a health record linkage study of females with localized (T1-3N0) or regional (T4 or N+) breast cancer [...]
Prescription drug monitoring programs (PDMP) are increasingly used to identify people prescribed high-dose opioids. However, little is known about whether PDMPs impact opioid agonist treatment (OAT) uptake, the gold standard for opioid use disorder. This study examined the impact of PDMP implementation on OAT initiation [...]
Controlled trials are the principal means of investigating the effects of therapeutic and prophylactic interventions. They can be designed to avoid biases, and so provide clear and reliable insights into 'what works' under ideal circumstances. Controlled trials can, however, also generate evidence to inform decisions [...]
A recent study showed that a moderately sized systematic review (index SR) could be completed in 2 weeks (2weekSR) by protecting time to solely focus on SR tasks and supported by systematic review automation (SRA) tools. Given that SRs are time and resource intensive that [...]
As the availability of genomic testing grows, variant interpretation will increasingly be performed by genomic generalists, rather than domain-specific experts. Demand is rising for laboratories to accurately classify variants in inherited cardiac condition (ICC) genes, including secondary findings. We analyse evidence for inheritance patterns, allelic [...]
Most health information does not meet the health literacy needs of our communities. Writing health information in plain language is time-consuming but the release of tools like ChatGPT may make it easier to produce reliable plain language health information. The objective of this study is [...]
People on the kidney waitlist are less informed about potential suspensions. Disparities may exist among those who are suspended and who return to the waitlist. We evaluated the patient journey after entering the waitlist, including suspensions and outcomes, and factors associated with these transitions.