Although placebo-controlled trials are considered the gold standard for evaluating the efficacy of healthcare interventions, they can be perceived to be controversial and challenging to conduct for surgical treatments. The SUcceSS trial is the first placebo-controlled trial of lumbar decompression surgery for symptomatic lumbar canal [...]
Short-stay joint replacement programmes are used in many countries but there has been little scrutiny of safety outcomes in the literature. We aimed to systematically review evidence on the safety of short-stay programmes versus usual care for total hip (THR) and knee replacement (KR), and [...]
Correction: Intensive Care Medicine https://doi.org/10.1007/s00134-023-07256-9 The original article has been corrected. The Authors apologize for the mistake. In the second paragraph of the second page, the first sentence “When using chemical sterilisation, such as ethyleneoxide gas or glutaraldehyde solution for bronchoscopes, reusable equipment will typically always [...]
Pain is one of the most burdensome symptoms in people with cancer, and opioid analgesics are considered the mainstay of cancer pain management. For this review, the authors evaluated the efficacy and toxicities of opioid analgesics compared with placebo, other opioids, nonopioid analgesics, and nonpharmacologic [...]
To the Editor: People with a history of melanoma have a higher risk of developing subsequent primary melanomas than the general population; however, a difference in outcome between those with multiple primary melanomas (MPMs) and a single primary melanoma (SPM) is not established. Using a [...]
On March 11, 2020, the World Health Organization declared the novel coronavirus disease 2019 (COVID-19) a global pandemic [1]. By Mid-March 2020, COVID-19 cases were accelerating in the US [2]. Daily life was disrupted on an unprecedented scale; by the end of the month, workplaces and schools [...]
Prosthetic joint infection (PJI) is a devastating complication of total hip arthroplasty (THA). This study aimed to determine if the anterior approach (AP) influenced the incidence of early PJI in THA compared to posterior approach (PP). Record linkage was performed between state-wide hospitalization data and [...]
Evidence indicates that a melanoma prevention program using personalized genomic risk provision and genetic counseling can affect prevention behaviors, including reducing sunburns in adults with no melanoma history. This analysis evaluated its longer-term cost-effectiveness from an Australian health system perspective.
In Australia, sterile gowns are considered an essential component of aseptic technique for all neuraxial procedures. However, guidelines from professional societies vary worldwide, and the Australian and New Zealand College of Anaesthetists' (ANZCA) guidelines are the oldest currently in use. In the USA, Canada and [...]
Mask induction of anesthesia for pediatric patients has included the use of nitrous oxide since the inception of pediatric anesthesia. However, the use of nitrous oxide precludes adequate preoxygenation. Additionally, pediatric physiology (less Functional Residual Capacity, higher oxygen consumption), increased risk of laryngospasm and lack [...]