Overuse is defined as provision of healthcare which is more likely to result in harm than good, and it is fast becoming a threat to human health and the sustainability of health systems worldwide. Overuse may, but not always, increase the risk of overdiagnosis, which [...]
Since 2020, hundreds of thousands of more deaths than expected have been observed across the globe. Amid the coronavirus 2019 (COVID-19) pandemic, current research priorities are to control the spread of infection and minimise loss of life. However, there may be future opportunities to learn [...]
This review found robust evidence to inform discussion of possible recalibration of diagnostic thresholds, or use of alternative labels, for low-risk prostate cancer. RCTs and cohort studies demonstrate that active surveillance is a safe option for very low-risk and low-risk prostate cancers, with extremely low [...]
CTPA use increased from 2005 to 2015 while diagnostic yield amongst ED patients decreased. The PE hospitalization rate also increased, while the outcome of PE mortality remained constant. Although this study cannot prove that overuse occurred, increasing CTPA use with decreasing diagnostic yield suggests an [...]
Breast density (BD) is an independent risk factor for breast cancer and reduces mammographic sensitivity. This study explored women’s responses and intentions if notified that they had dense breasts.
Growing evidence suggests overuse of medications is widespread within low- and middle-income countries, across multiple drug classes, with few data of solutions from randomized trials. Opportunities exist to build collaborations to rigorously develop and evaluate potential solutions to reduce overuse of medications.
Objectives: To determine the total annual screening and further-investigation costs of investigating false-positive and true-positive mammograms in the Australian population breast-screening program.
Overuse is defined as provision of healthcare which is more likely to result in harm than good, and it is fast becoming a threat to human health and the sustainability of health systems worldwide. Overuse may, but not always, increase the risk of overdiagnosis, which [...]
Overdiagnosis and overuse of healthcare services harm individuals, take resources that could be used to address underuse, and threaten the sustainability of health systems. These problems are attracting increasing attention in low-income and middle-income countries (LMICs). Unaware of any review of relevant evidence, we conducted [...]
This framework focuses on the importance of the consideration of the downstream intermediate and long-term health outcomes when a change to a screening program is introduced. The authors present a methodology for utilising the relationship between screen-detected and interval cancer rates to infer the benefits [...]