The objective of this study is to quantify the proportion of melanoma diagnoses (invasive and in situ) in the USA that might be overdiagnosed. In this ecological study, incidence and mortality data were collected from the Surveillance, Epidemiology and End Results 9 registries database. DevCan [...]
The growing number of Direct To Consumer (DTC) tests available for direct purchase online in Australia purport to empower consumers with choice and convenience of access. The categorisation of clinical utility developed in this study shows the majority of currently available products lack clear benefits [...]
To the Editor: Good clinical decisions should weigh benefits against harms. The recent JAMA Insights article on gestational diabetes mellitus (GDM) focused on the potential benefits of increased detection and treatment of GDM and subsequent promotion of cardiovascular health.1 Unmentioned were the potential detrimental effects of overdiagnosis [...]
Many of us have done countless rapid antigen tests (RATs) over the course of the pandemic. Testing ourselves at home has become second nature. But there’s also a growing worldwide market in medical tests sold online directly to the public. These are “direct-to-consumer” tests, and [...]
You order a computed tomography pulmonary angiogram (CTPA) for a patient with suspected pulmonary thromboembolism. The radiology report states that no pulmonary thromboembolism is seen but notes an unrelated lung nodule. What should you do with this incidental finding, or “incidentaloma”?
There is little evidence on the balance between potential benefits and harms of mammography screening in women 75 years and older. The aim of this systematic review was to synthesise the evidence on the outcomes of mammography screening in women aged 75 years and older. [...]
The VALID BP project was initiated to increase the availability of validated blood pressure measuring devices (BPMDs). The goal is to eliminate non validated BPMDs and minimise over- and underdiagnosis of hypertension caused by inaccurate readings. This study was undertaken to assess the potential return [...]
The objective of this study is to evaluate the strength of the evidence for, and the extent of, overdiagnosis in non-cancer conditions. We systematically searched for studies investigating overdiagnosis in non-cancer conditions. Using the 'Fair Umpire' framework to assess the evidence that cases diagnosed by [...]
Internationally, screening programmes and clinical practice guidelines recommend when older adults should stop cancer screening using upper age limits, but it is unknown how older adults view these recommendations. The obective of this study is to examine older adults’ views and experiences about continuing or [...]
The present study examines the patterns of hospital and emergency department services in conjunction with both pre and post diagnostic periods of CT use, which has not been evaluated to date in adult patients with cancer. The cohort makes use of whole of population data [...]