On the basis of evidence from the Dense RCT, the recommendation for broader offer of MRI screening for those with dense breasts may be considered premature by some but tardy by others – what cannot be contested however is that screening tests should be acceptable, [...]
We have come a long way, from referring to HCM as a “tumour of the heart” to understanding the complex nature of this genetic disorder which targets the most basic functional unit of the heart, i.e. the sarcomere. Genetic testing on HCM is now common [...]
There are informative diagnostic tests for the disc, sacroiliac joint, and facet joint (only one test). The evidence suggests a diagnosis may be possible for some patients with low back pain, potentially guiding targeted and specific treatment approaches.
Many administrative health data-based studies define patient cohorts using procedure and diagnosis codes. The impact these criteria have on a study’s final cohort is not always transparent to co-investigators or other audiences if access to the research data is restricted. We developed a SAS and [...]
The interpretation of the risk ratio as an effect measure in a clinical trial is naïve and better replaced by its interpretation as a likelihood ratio. The ratio of the complementary risk ratio's (or likelihood ratio's) is what should actually be interpreted as an effect [...]
To compare and contrast the diagnostic codes for spinal causes of low back pain (LBP) in 3 disease classification systems (International Classification of Diseases [ICD]-10, International Classification of Primary Care [ICPC]-2 PLUS and Systematized Nomenclature of Medicine Clinical Terms - Australia [SNOMED CT-AU]) and consider [...]